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1703 Publications visible to you, out of a total of 1703
Gravitational wave emission from dynamical stellar interactions

Abstract

Not specified

Authors: Javier Morán-Fraile, Fabian R. N. Schneider, Friedrich K. Röpke, Sebastian T. Ohlmann, Rüdiger Pakmor, Theodoros Soultanis, Andreas Bauswein

Date Published: 1st Apr 2023

Publication Type: Journal

Improved insights into the SABIO-RK database via visualization.

Abstract (Expand)

SABIO-RK is a database for biochemical reactions and their kinetics. Data in SABIO-RK are inherently multidimensional and complex. The complex relationships between the data are often difficult to … follow or even not represented when using standard tabular views. With an increasing number of data points the mismatch between tables and insights becomes more obvious, and getting an overview of the data becomes harder. Such complex data benefit from being presented using specially adapted visual tools. Visualization is a natural and user-friendly way to quickly get an overview of the data and to detect clusters and outliers. Here, we describe the implementation of a variety of visualization concepts into a common interface within the SABIO-RK biochemical reaction kinetics database. For that purpose, we use a heat map, parallel coordinates and scatter plots to allow the interactive visual exploration of general entry-based information of biochemical reactions and specific kinetic parameter values. Database URL https://sabiork.h-its.org/.

Authors: D. Dudas, U. Wittig, M. Rey, A. Weidemann, W. Muller

Date Published: 31st Mar 2023

Publication Type: Journal

Vision for the Virtual Human Twin and Roadmap Outline

Abstract (Expand)

The present document is the first written presentation of the Virtual Human Twin (VHT) vision as it has been prepared by the EDITH consortium and discussed with select representatives of the wider … ecosystem. After a brief statement on the genesis of the vision, the document is composed of two main parts: the outline of the VHT roadmap and the elaboration of the vision for the integrated Virtual Human Twin.

Author: Gerhard Mayer, Martin Golebiewski

Date Published: 31st Mar 2023

Publication Type: Misc

Energetics and kinetics of membrane permeation of photoresists for bioprinting

Abstract

Not specified

Authors: Lucas Diedrich, Matthias Brosz, Tobias Abele, Salome Steinke, Frauke Gräter, Kerstin Göpfrich, Camilo Aponte-Santamaría

Date Published: 28th Mar 2023

Publication Type: Journal

Glycosaminoglycans: What Remains To Be Deciphered?

Abstract

Not specified

Authors: Serge Perez, Olga Makshakova, Jesus Angulo, Emiliano Bedini, Antonella Bisio, Jose Luis de Paz, Elisa Fadda, Marco Guerrini, Michal Hricovini, Milos Hricovini, Frederique Lisacek, Pedro M. Nieto, Kevin Pagel, Giulia Pairardi, Ralf Richter, Sergey A. Samsonov, Romain A. Vivès, Dragana Nikitovic, Sylvie Ricard Blum

Date Published: 27th Mar 2023

Publication Type: Journal

Convergence of forecast distributions in a 100,000‐member idealised convective‐scale ensemble

Abstract

Not specified

Authors: Kirsten I. Tempest, George C. Craig, Jonas R. Brehmer

Date Published: 22nd Mar 2023

Publication Type: Journal

The power and limitations of species tree-aware phylogenetics

Abstract (Expand)

Abstract Species tree-aware phylogenetic methods model how gene trees are generated along the species tree by a series of evolutionary events, including the duplication, transfer and loss of genes. …fer and loss of genes. Over the past ten years these methods have emerged as a powerful tool for inferring and rooting gene and species trees, inferring ancestral gene repertoires, and studying the processes of gene and genome evolution. However, these methods are complex and can be more difficult to use than traditional phylogenetic approaches. Method development is rapid, and it can be difficult to decide between approaches and interpret results. Here, we review ALE and GeneRax, two popular packages for reconciling gene and species trees, explaining how they work, how results can be interpreted, and providing a tutorial for practical analysis. It was recently suggested that reconciliation-based estimates of duplication and transfer frequencies are unreliable. We evaluate this criticism and find that, provided parameters are estimated from the data rather than being fixed based on prior assumptions, reconciliation-based inferences are in good agreement with the literature, recovering variation in gene duplication and transfer frequencies across lineages consistent with the known biology of studied clades. For example, published datasets support the view that transfers greatly outnumber duplications in most prokaryotic lineages. We conclude by discussing some limitations of current models and prospects for future progress. Significance statement Evolutionary trees provide a framework for understanding the history of life and organising biodiversity. In this review, we discuss some recent progress on statistical methods that allow us to combine information from many different genes within the framework of an overarching phylogenetic species tree. We review the advantages and uses of these methods and discuss case studies where they have been used to resolve deep branches within the tree of life. We conclude with the limitations of current methods and suggest how they might be overcome in the future.

Authors: Tom A. Williams, Adrian A. Davin, Benoit Morel, Lénárd L. Szánthó, Anja Spang, Alexandros Stamatakis, Philip Hugenholtz, Gergely J. Szöllősi

Date Published: 17th Mar 2023

Publication Type: Journal

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