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1702 Publications visible to you, out of a total of 1702

Abstract

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Authors: Melvin M. Moreno, Fabian R. N. Schneider, Friedrich K. Röpke, Sebastian T. Ohlmann, Rüdiger Pakmor, Philipp Podsiadlowski, Christian Sand

Date Published: 1st Nov 2022

Publication Type: Journal

Abstract (Expand)

Abstract Summary The evaluation of phylogenetic inference tools is commonly conducted on simulated and empirical sequence data alignments. An open question is how representative these alignments aretion is how representative these alignments are with respect to those, commonly analyzed by users. Based upon the RAxMLGrove database, it is now possible to simulate DNA sequences based on more than 70, 000 representative RAxML and RAxML-NG tree inferences on empirical datasets conducted on the RAxML web servers. This allows to assess the phylogenetic tree inference accuracy of various inference tools based on realistic and representative simulated DNA alignments. We simulated 20, 000 MSAs based on representative datasets (in terms of signal strength) from RAxMLGrove, and used 5, 000 datasets from the TreeBASE database, to assess the inference accuracy of FastTree2, IQ-TREE2, and RAxML-NG. We find that on quantifiably difficult-to-analyze MSAs all of the analysed tools perform poorly, such that the quicker FastTree2, can constitute a viable alternative to infer trees. We also find, that there are substantial differences between accuracy results on simulated and empirical data, despite the fact that a substantial effort was undertaken to simulate sequences under as realistic as possible settings. Contact Dimitri Höhler, dimitri.hoehler@h-its.org

Authors: Dimitri Höhler, Julia Haag, Alexey M. Kozlov, Alexandros Stamatakis

Date Published: 1st Nov 2022

Publication Type: Journal

Abstract

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Authors: Lukas Hubner, Demian Hespe, Peter Sanders, Alexandros Stamatakis

Date Published: 1st Nov 2022

Publication Type: Journal

Abstract

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Authors: Melvin M. Moreno, Fabian R. N. Schneider, Friedrich K. Röpke, Sebastian T. Ohlmann, Rüdiger Pakmor, Philipp Podsiadlowski, Christian Sand

Date Published: 1st Nov 2022

Publication Type: Journal

Abstract

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Authors: Johannes Bracher, Daniel Wolffram, Jannik Deuschel, Konstantin Görgen, Jakob L. Ketterer, Alexander Ullrich, Sam Abbott, Maria V. Barbarossa, Dimitris Bertsimas, Sangeeta Bhatia, Marcin Bodych, Nikos I. Bosse, Jan Pablo Burgard, Lauren Castro, Geoffrey Fairchild, Jochen Fiedler, Jan Fuhrmann, Sebastian Funk, Anna Gambin, Krzysztof Gogolewski, Stefan Heyder, Thomas Hotz, Yuri Kheifetz, Holger Kirsten, Tyll Krueger, Ekaterina Krymova, Neele Leithäuser, Michael L. Li, Jan H. Meinke, Błażej Miasojedow, Isaac J. Michaud, Jan Mohring, Pierre Nouvellet, Jedrzej M. Nowosielski, Tomasz Ożański, Maciej Radwan, Franciszek Rakowski, Markus Scholz, Saksham Soni, Ajitesh Srivastava, Tilmann Gneiting, Melanie Schienle

Date Published: 31st Oct 2022

Publication Type: Journal

Abstract

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Authors: Marcus Fabiano de Almeida Mendes, Marcelo de Souza Bragatte, Priscila Vianna, Martiela Vaz de Freitas, Ina Pöhner, Stefan Richter, Rebecca C. Wade, Francisco Mauro Salzano, Gustavo Fioravanti Vieira

Date Published: 28th Oct 2022

Publication Type: Journal

Abstract

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Authors: Johannes Witt, Saskia Haupt, Aysel Ahadova, Lena Bohaumilitzky, Vera Fuchs, Alexej Ballhausen, Moritz Jakob Przybilla, Michael Jendrusch, Toni T. Seppälä, Daniel Fürst, Thomas Walle, Elena Busch, Georg Martin Haag, Robert Hüneburg, Jacob Nattermann, Magnus von Knebel Doeberitz, Vincent Heuveline, Matthias Kloor

Date Published: 25th Oct 2022

Publication Type: Journal

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