Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase

Abstract:
No abstract specified

SEEK ID: https://publications.h-its.org/publications/565

DOI: 10.1021/acs.jmedchem.5b00137

Research Groups: Molecular and Cellular Modeling

Publication type: Journal

Journal: Journal of Medicinal Chemistry

Citation: J. Med. Chem. 58(8):3572-3581

Date Published: 13th Apr 2015

Registered Mode: by DOI

Authors: Outi M. H. Salo-Ahen, Anna Tochowicz, Cecilia Pozzi, Daniela Cardinale, Stefania Ferrari, Yap Boum, Stefano Mangani, Robert M. Stroud, Puneet Saxena, Hannu Myllykallio, Maria Paola Costi, Glauco Ponterini, Rebecca C. Wade

Citation
Salo-Ahen, O. M. H., Tochowicz, A., Pozzi, C., Cardinale, D., Ferrari, S., Boum, Y., Mangani, S., Stroud, R. M., Saxena, P., Myllykallio, H., Costi, M. P., Ponterini, G., & Wade, R. C. (2015). Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase. In Journal of Medicinal Chemistry (Vol. 58, Issue 8, pp. 3572–3581). American Chemical Society (ACS). https://doi.org/10.1021/acs.jmedchem.5b00137
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Created: 6th Dec 2019 at 13:54

Last updated: 5th Mar 2024 at 21:24

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