Publications

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73 Publications visible to you, out of a total of 73

Abstract

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Authors: Ghulam A. Qadir, Ying Sun

Date Published: 2025

Publication Type: Journal

Abstract

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Authors: Pratik Nag, Yiping Hong, Sameh Abdulah, Ghulam A. Qadir, Marc G. Genton, Ying Sun

Date Published: 12th Sep 2024

Publication Type: Journal

Abstract

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Authors: Eva–Maria Walz, Peter Knippertz, Andreas H. Fink, Gregor Köhler, Tilmann Gneiting

Date Published: 1st Sep 2024

Publication Type: Journal

Abstract

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Authors: Timo Dimitriadis, Tilmann Gneiting, Alexander I. Jordan, Peter Vogel

Date Published: 31st May 2024

Publication Type: Journal

Abstract

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Authors: Velma K. Lopez, Estee Y. Cramer, Robert Pagano, John M. Drake, Eamon B. O'Dea, Madeline Adee, Turgay Ayer, Jagpreet Chhatwal, Ozden O. Dalgic, Mary A. Ladd, Benjamin P. Linas, Peter P. Mueller, Jade Xiao, Johannes Bracher, Alvaro J. Castro Rivadeneira, Aaron Gerding, Tilmann Gneiting, Yuxin Huang, Dasuni Jayawardena, Abdul H. Kanji, Khoa Le, Anja Mühlemann, Jarad Niemi, Evan L. Ray, Ariane Stark, Yijin Wang, Nutcha Wattanachit, Martha W. Zorn, Sen Pei, Jeffrey Shaman, Teresa K. Yamana, Samuel R. Tarasewicz, Daniel J. Wilson, Sid Baccam, Heidi Gurung, Steve Stage, Brad Suchoski, Lei Gao, Zhiling Gu, Myungjin Kim, Xinyi Li, Guannan Wang, Lily Wang, Yueying Wang, Shan Yu, Lauren Gardner, Sonia Jindal, Maximilian Marshall, Kristen Nixon, Juan Dent, Alison L. Hill, Joshua Kaminsky, Elizabeth C. Lee, Joseph C. Lemaitre, Justin Lessler, Claire P. Smith, Shaun Truelove, Matt Kinsey, Luke C. Mullany, Kaitlin Rainwater-Lovett, Lauren Shin, Katharine Tallaksen, Shelby Wilson, Dean Karlen, Lauren Castro, Geoffrey Fairchild, Isaac J. Michaud, Dave Osthus, Jiang Bian, Wei Cao, Zhifeng Gao, Juan Lavista Ferres, Chaozhuo Li, Tie-Yan Liu, Xing Xie, Shun Zhang, Shun Zheng, Matteo Chinazzi, Jessica T. Davis, Kunpeng Mu, Ana Pastory y Piontti, Alessandro Vespignani, Xinyue Xiong, Robert Walraven, Jinghui Chen, Quanquan Gu, Lingxiao Wang, Pan Xu, Weitong Zhang, Difan Zou, Graham Casey Gibson, Daniel Sheldon, Ajitesh Srivastava, Aniruddha Adiga, Benjamin Hurt, Gursharn Kaur, Bryan Lewis, Madhav Marathe, Akhil Sai Peddireddy, Przemyslaw Porebski, Srinivasan Venkatramanan, Lijing Wang, Pragati V. Prasad, Jo W. Walker, Alexander E. Webber, Rachel B. Slayton, Matthew Biggerstaff, Nicholas G. Reich, Michael A. Johansson

Date Published: 6th May 2024

Publication Type: Journal

Abstract (Expand)

Motivation: Genotype datasets typically contain a large number of single nucleotide polymorphisms for a comparatively small number of individuals. To identify similarities between individuals and to infer an individual’s origin or membership to a cultural group, dimensionality reduction techniques are routinely deployed. However, inherent (technical) difficulties such as missing or noisy data need to be accounted for when analyzing a lower dimensional representation of genotype data, and the uncertainty of such an analysis should be reported in all studies. However, to date, there exists no stability estimation technique for genotype data that can estimate this uncertainty. Results: Here, we present Pandora, a stability estimation framework for genotype data based on bootstrapping. Pandora computes an overall score to quantify the stability of the entire embedding, perindividual support values, and deploys a k-means clustering approach to assess the uncertainty of assignments to potential cultural groups. In addition to this bootstrap-based stability estimation, Pandora offers a sliding-window stability estimation for whole-genome data. Using published empirical and simulated datasets, we demonstrate the usage and utility of Pandora for studies that rely on dimensionality reduction techniques. Data and Code: Availability Pandora is available on GitHub https://github.com/tschuelia/Pandora. All Python scripts and data to reproduce our results are available on GitHub https://github.com/tschuelia/PandoraPaper.

Authors: Julia Haag, Alexander I. Jordan, Alexandros Stamatakis

Date Published: 15th Mar 2024

Publication Type: Journal

Abstract

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Authors: Jack Fosten, Daniel Gutknecht, Marc-Oliver Pohle

Date Published: 12th Mar 2024

Publication Type: Journal

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