Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1

Pöhner, I., Quotadamo, A., Panecka-Hofman, J., Luciani, R., Santucci, M., Linciano, P., Landi, G., Di Pisa, F., Dello Iacono, L., Pozzi, C., Mangani, S., Gul, S., Witt, G., Ellinger, B., Kuzikov, M., Santarem, N., Cordeiro-da-Silva, A., Costi, M. P., Venturelli, A., & Wade, R. C. (2022). Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. In Journal of Medicinal Chemistry (Vol. 65, Issue 13, pp. 9011–9033). American Chemical Society (ACS). https://doi.org/10.1021/acs.jmedchem.2c00232