A Blueprint for High Affinity SARS-CoV-2 Mpro Inhibitors from Activity-Based Compound Library Screening Guided by Analysis of Protein Dynamics

Gossen, J., Albani, S., Hanke, A., Joseph, B. P., Bergh, C., Kuzikov, M., Costanzi, E., Manelfi, C., Storici, P., Gribbon, P., Beccari, A. R., Talarico, C., Spyrakis, F., Lindahl, E., Zaliani, A., Carloni, P., Wade, R. C., Musiani, F., Kokh, D. B., & Rossetti, G. (2021). A Blueprint for High Affinity SARS-CoV-2 Mpro Inhibitors from Activity-Based Compound Library Screening Guided by Analysis of Protein Dynamics. In ACS Pharmacology & Translational Science (Vol. 4, Issue 3, pp. 1079–1095). American Chemical Society (ACS). https://doi.org/10.1021/acsptsci.0c00215